To test this hypothesis, the team set out to identify individuals who had never been exposed to the virus, track their EBV status through time and see if their chance of developing multiple sclerosis increased following exposure. So to identify people with no prior EBV exposure, the team combed through a unique dataset curated by the U. Department of Defense.
The Department of Defense maintains a repository of serum, the yellowish, fluid portion of blood , sampled from military personnel. At the start of their service, and about every two years afterward, active-duty military members provide serum for HIV screening, and any residual serum from the tests gets placed in the repository. Serum contains antibodies, and thus, these stored samples provided the researchers with a way to check each person's EBV status through time, by checking for antibodies against the virus.
The team then used this data to investigate the potential link between EBV status and the onset of multiple sclerosis. Of course, their data only focused on these individuals who became exposed in their early 20s, rather than during childhood.
Using medical records, they identified individuals who developed multiple sclerosis during the study period and who had provided at least three serum samples prior to their diagnosis. They found that 35 of these individuals had tested negative for EBV-specific antibodies at their initial serum sampling, but in time, all but one person became exposed to the virus.
So out of the caught EBV before developing multiple sclerosis. Mononucleosis: Can it recur? Products and services. Can mononucleosis recur? I thought that once you got mono you couldn't get it again. Thank you for subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry.
Show references AskMayoExpert. Epstein-Barr virus infection. Mayo Clinic; Sullivan JL. Clinical manifestations and treatment of Epstein-Barr infection. Accessed Dec. Aronson MD. So are you contagious during this time? Is it possible to contract EBV more than once? And does that mean you can get mono…. Mono rash is one symptom of the viral infection, mononucleosis.
The more common symptoms are fever, fatigue, and a sore throat. If you have these…. Epstein-Barr is one of the most common viruses that affects humans. We'll go over the basics of Epstein-Barr virus infections and explore the link…. A mononucleosis spot test will determine if you have the Epstein-Barr virus.
Find out what to expect and what the results mean. Technically, yes, mono can be considered a sexually transmitted infection STI. The virus that…. Mono treatment consists mainly of rest, fluids, and pain relief. Since mono is a viral infection, it's usually caused by the Epstein-Bar virus…. Learn about their…. Health Conditions Discover Plan Connect. Medically reviewed by Stacy Sampson, D. Treatment Symptoms Home remedies How long does it last? Preventing mono Takeaway Mono mononucleosis is also called infectious mononucleosis.
Mono usually affects teenagers and young adults, but anyone can get it. Like the common cold, a virus causes mono. It may take a few months before you completely recover from mono. Because your spleen may become enlarged as a result of infectious mononucleosis, you should avoid contact sports until you fully recover.
Participating in contact sports can be strenuous and may cause the spleen to rupture. Laboratory tests are not usually needed to diagnose infectious mononucleosis. However, specific laboratory tests may be needed to identify the cause of illness in people who do not have a typical case of infectious mononucleosis.
The blood work of patients who have infectious mononucleosis due to EBV infection may show—. Skip directly to site content Skip directly to page options Skip directly to A-Z link.
Epstein-Barr Virus and Infectious Mononucleosis. Section Navigation.
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